How to activate a SEPARATE instance of excel???

Hello everyone! I am new to the forums (and "somewhat" to VBA as well) so I apologize if this is posted in the wrong area. Essentially I have multiple instances of excel open. I have one instance of excel (lets refer to as workbook1) that I want to run 5 other instance (lets refer to them as workbook2, 3, 4, etc.). I have tried the following:

Applications.Run...

Set wb1 = wokbooks.open(filename)
wb1.select ....

etc...

All of which work, but they run the other macros IN THE SAME INSTANCE as the one I'm calling it from. I don't want this. I want them to run in there separate instances. Is there any (preferably simple) way I can do this? Hopefully my question is clear.

Thanks!